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To calculate the sensitivity (true positive rate) and specificity (true negative rate) of each in vitro liver test system for detection of carcinogenic (Table 3) or in vitro/in vivo mutagenic NAs, existing rodent cancer data or in vitro and in vivo mutagenicity data were used as supposed truth (see Table 1 and 4)

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To view a copy of this license, visit About this article Cite this article Wang, XY., Wang, B