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Obesity and hyperlactatemia was negatively associated with AVP-response (adjusted Odds Ratio [aOR] 0.30, 95%CI 0.140.65 and aOR 0.86, 95%CI 0.750.99, respectively), while a NE infusion rate 0.30 g/kg/min showed positive odds of AVP response (aOR 2.33, 95%CI 1.065.14)

CJC-1295 pharmacokinetic data are derived from small published human trials reporting prolonged half-life with the DAC modification

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