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Description

Targetting ferroptosis for blood cell-related diseases

Once activated, AMPK suppresses anabolic processes such as lipid and protein synthesis, while enhancing catabolic pathways, including FAO and autophagy, to restore energy homeostasis

M.JonkersJ

Mira Meeus, Jo Nijs, Linda Hermans, Dorien Goubert & Patrick Calders (2013) The role of mitochondrial dysfunctions due to oxidative and nitrosative stress in the chronic pain or chronic fatigue syndromes and fibromyalgia patients: peripheral and central mechanisms as therapeutic targets?, Expert Opinion on Therapeutic Targets, 17:9, 1081-1089, DOI: 10.1517/14728222.2013.818657 Myhill S, Booth NE, McLaren-Howard J