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For example, about one in every 15 individuals will show an altered response to doses of beta blockers, a class of medication often prescribed for hypertension and metabolized by the cytochrome P450 enzyme system 17,30

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colis own periplasmic proteins The observed influence of GSH on growth phenotypes (Supplementary figure 3) suggests that our previous observations of disulfide bond formation in heterologously expressed roGFP-based redox sensors also apply to endogenous DsbA substrates