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This ATP release by RGCs is associated with glial cell activation and increased expression of proinflammatory cytokines such as TNF-, IL-1, or IL-6 (Silverman et al., 2009)

A random effect of ID (sequence) was also included

Long-term stability, spray device compatibility, and preservation all require attention

534 Increasing evidence also points towards the role of glutamate, released by astrocytes, as a gliotransmitter to regulate synaptic transmission and plasticity