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For laboratory research use only

PVP can also interact with amino acids, proteins, and other secondary metabolites, but its affinity for those compounds is generally lower than phenolic compounds [51]

Notably, surgically removing and selectively destroying the vagal afferent nerves can completely suppress the orexigenic effects of peripheral ghrelin, while vagotomized rodents can retain their responsiveness to centrally injected ghrelin (72, 73)