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doi: 10.3389/fnmol.2022.866700 232 ZouJ.LiY.LiaoN.LiuJ.ZhangQ.LuoM.et al

This strategy overcomes the half-life limitations of traditional drugs (e.g., continuous siRNA expression for over 2 weeks), enabling targeted, long-lasting therapeutic gene expression and adaptive repair for IVD regeneration (Ma et al., 2024