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BPC-157 is a synthetic peptide modeled on a sequence associated with human gastric juice research, not an approved therapeutic peptide drug [1] [3]

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Granzyme B as a novel factor involved in cardiovascular diseases

For instance, chronic doxorubicin (DOX) intervention can also lead to cardiomyocyte aging, suggesting that the aging mechanism shares many irreversible stress factors with the cardiac injury pathway, such as decreased Sirtuins expression, increased p38 mitogen-activated protein kinases (p38MAPK) signaling, and decreased antioxidant enzyme levels represented by MnSOD [21, 22]