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Furthermore, administration of melatonin along with all-trans-retinoic acid (RXR and RAR) in MCF-7 cells induced the rate of apoptosis, which is mediated by increased expression of pro-apoptotic protein Bax and downregulation of TGF-1 and Bcl-2 (anti-apoptotic protein) expression [61]

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found that BV had a cytotoxic impact on glioblastoma A1235 cells at 20 g/mL (Gajski et al., 2016)