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Description

Although lipogenesis occurs in the cytoplasm (ER), mitochondria are the primary source of acetyl-CoA, the building block for lipogenesis in the liver

The results from five replicates were calculated and expressed as stimulation index (SI)

Most striking

Mechanisms investigated Metabolic-pathway research converges on a small set of enzymatic and receptor targets, and these compounds map onto different ones they are not interchangeable: NNMT inhibition (5-Amino-1MQ): studied as a small-molecule inhibitor of nicotinamide N-methyltransferase, an enzyme implicated in cellular NAD/SAM metabolism