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Clin J Sport Med

While the exact role of oxidants in disease onset is not always clear, OS has garnered significant attention as a factor in human diseases and has been the focus of extensive research

doi: 10.1128/mSystems.00013-15 180 QuraishiMNAcharjeeABeggsADHorniblowRTselepisCGkoutosGet al

HIV-1 proteins, including Tat, Nef, Vpr, protease, and gp120, modulate ROS-generating systems and induce oxidative stress, thereby promoting the expression of viral genes and proinflammatory lymphokines 114,115,116