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10.1242/jcs.093849 58 KaganV.JiangJ.HuangZ.TyurinaY.DesbourdesC.Cottet-RousselleC.et al (2016)

If SPIONs are appropriately coated, hydrophilic and stable NPs can be obtained, preserving their superparamagnetic behavior

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Early reports that Kupffer cell-induced oxidant stress and peroxynitrite formation may cause APAP-induced injury [92, 93] were questioned as the data could not be reproduced [9496], NADPH oxidase-deficient mice were not protected [97, 98] and mitochondria in centrilobular hepatocytes were identified as the main source of superoxide and peroxynitrite under these conditions [72, 99]