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Approximately 2% of AD cases are caused by familial AD, whereas the remaining 98% are caused by sporadic AD

doi: 10.1016/S0140-6736(16)00578-X 123 TagamiT.TosaR.OmuraM.FukushimaH.KanekoT.EndoT.et al

In experimental models of OS, curcumin exhibits inhibitory effects on the p53/p21 signaling pathway, resulting in a reduction of OS by suppressing p53 expression [171]