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The four hero molecules I have endorsed for inclusion in the Syntha-Pep formulation, GHK-Cu, sh-Oligopeptide-1 (the EGF analog), PDRN, and a multi-molecular-weight HA system, are the four with the strongest peer-reviewed clinical evidence supporting their use specifically in a delivery-enhanced context

Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs

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GHK is a copper-binding peptide that occurs naturally in the human body