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Since varying sample efficiencies occur between these two techniques, integrating LCMS and MSI is highly encouraged to elucidate critical metabolic interactions

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B cells Acetaldehyde and other intermediate products produced during alcohol metabolism are immunogenic and can bind to proteins in hepatocytes, forming new antigenic epitopes [86]

T Serikawa, O Fujii, and other staff members of Institute of Laboratory Animals, Kyoto University, Graduate School of Medicine, for careful animal maintenance, M Sugimoto for secretarial assistance in the preparation of this manuscript, C Sayo, A Yamaguchi, T Matsushita, and I Fujiwara for their technical assistance, Cell Resource Center for Biomedical Research, Institute of Development, Aging and Cancer, Tohoku University and Dr