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Mol Genet Metab 100:2936 Froese DS, Zhang J, Healy S, Gravel RA (2009) Mechanism of vitamin B12-responsiveness in cblC methylmalonic aciduria with homocystinuria

Clinical observations revealed no o redness or swelling at the injection site or in the affected joint

Rotate Injection Sites: To reduce irritation and prevent localized pain or swelling, vary your injection sites

The standard B12 injection protocol typically follows a structured schedule: Initial phase: 100 mcg daily for one week Secondary phase: Every other day for seven doses Maintenance phase: Monthly injections of 100-200 mcg [11] Patients may receive their injections in the thigh, stomach, or upper arm, rotating injection sites weekly [12]