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Work through these ten items before the claim leaves your system: Confirm no definitive diagnosis exists in the assessment before using R74.01 as primary Verify the provider named ALT, AST, or both by enzyme name, not just "elevated liver enzymes" or "elevated LFTs" Confirm numeric lab values with collection dates appear in the assessment or plan Confirm the plan includes a follow-up action with a documented clinical link to the enzyme finding When DILI is suspected or confirmed, confirm K71.x plus a T36-T50.x5 adverse effect code are both present When alcohol use is confirmed as the cause, confirm current use is documented and K70.x is assigned When imaging confirms fatty infiltration, confirm the transition from R74.01 to K76.0 has happened Code to the 5th digit minimum, R74.0 is non-billable and R74.01 is required Confirm the diagnosis pointer in 837P Loop 2400 links R74.01 to the specific CPT billed Verify the payer-specific LCD for CPT 80076 before submission to confirm R74.01 is a covered diagnosis Practices that clear these ten items before submission watch denial rates on liver enzyme claims drop below 3%