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doi: 10.3892/mmr.2021.11956 277 ShahBKhanRShahWAftabAKhanMDilSet al

Hormetins activate the Nrf2 pathway, upregulating the expression of genes encoding antioxidant enzymes, such as glutathione peroxidase and superoxide dismutase

Nitric oxide induces conformational and functional modifications of wild-type p53 tumor suppressor protein

As for women, a randomized, doubleblind, placebocontrolled clinical trial involving 150 women (aged 18-39) with clomiphene-resistant PCOS found that adding NAC (1.2 grams/day for five days starting on day three of the cycle) to clomiphene citrate significantly increased both ovulation and pregnancy rates