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Science 291 , 17931796 (2001)

Research interest nonetheless expanded considerably through the 1980s and 1990s, as investigators began exploring DSIP's broader neuroendocrine roles, including its interactions with the HPA axis, circadian timing systems, and stress-response pathways, establishing the compound as a multifunctional regulatory neuropeptide whose biological significance extends well beyond its original sleep-focused characterization

BPC-157, or Body Protection Compound-157, is a synthetic peptide derived from a protein found naturally in gastric juice