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In in vitro experiments, GDNF treatment of midbrain dopaminergic neurons significantly increases mitochondrial DNA copy number and enhances mitochondrial membrane potentialan effect dependent on Ret-mediated activation of PGC-1 [75]

For example, GshB has two protein clusters associated with it (PRK12458 and PRK05246), so if the first hit from RPS-Blast for a protein was any one of these clusters, the protein was assumed to be GshB

They form a complex network of interregulation through shared mitochondrial functional networks and oxidative stress signals

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