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The following primary antibodies were used for immunostaining in this study: rabbit anti-GNPT subunit (1:100, homemade), rabbit anti-LYSET (1:100, HPA-48559, Millipore-Sigma), mouse anti-GM130 (1:100, 610822, BD Biosciences), and anti-GCN4 [IPI-C11L34] (1:100, 218104-rAb, Addgene), mouse anti-IL-2Ra (1:100, 05-170, Millipore-Sigma)

Consequently, broad CAF-targeting therapies must be approached with caution, as removing all fibroblasts can inadvertently dampen immune surveillance, whereas targeting the right subtype can alleviate immunosuppression