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Parkinson's disease has increased at a pace that genetics alone cannot explain., As @raydorseymd explains, only a minority of cases are linked to known genetic risk factors. For the vast majority of Parkinson's disease linked parkin mutation disrupts recycling of synaptic vesicles in human dopaminergic neurons ScienceDirect The irony of Parkinson's disease: Converging mechanisms of redox imbalance and ferroptosis ScienceDirect Parkinson's Focus On Prevention David Perlmutter M.D.
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