lysosome glutathione A rational design of a cancer-specific and lysosome-targeted fluorescence nanoprobe for imaging in living cells Lysosomal cystine governs ferroptosis sensitivity

Lysosomal cystine governs ferroptosis sensitivity in cancer via cysteine stress response ScienceDirect Ferroptosis regulation in lysosome Lysosomal iron and cathepsin B contribute to ferroptotic cell death. Lysosomal cyst(e)ine can be mobilized to maintain glutathione synthesis and glutathione peroxidase 4 activity, thereby limiting lipid peroxidation. Key Mechanisms in Lysosome Stability, Degradation and Repair PMC Why Do We Need Liposomal Glutathione? Researched Nutritionals

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