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Overall, these observations suggest that OEB regulated lipid metabolism through increasing the abundance of Akkermansia and Parabacteroides

Topical application Topical delivery makes intuitive sense for a skin condition

Additionally, although authentic Cu 2+ receptors remain unidentified, our RNA-seq revealed several DEGs encoding membrane proteins such as receptor-like kinases (RLKs), wall-associated kinases (WAKLs), LRR-RLKs, and ZIP transporters ( Supplementary Table S3 ) as candidate upstream Cu 2+ -perception components for future validation

The cardiac injury arises from multiple interrelated mechanisms, including oxidative stress, mitochondrial dysfunction, apoptosis, inflammation, iron accumulation, topoisomerase II inhibition, and dysfunctional autophagy/mitophagy (Zhang et al., 2012