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Description

497 Tubeimoside-I, a heat shock protein inhibitor, has been reported to synergize with Oxaliplatin in CRC by increasing ROS levels, downregulating HSPD1, and upregulating ER stress and MAPK pathways, thereby enhancing the anticancer effects of Oxaliplatin

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IHC analysis further confirmed that STK38 loss led to a reduction in RIPK1 S309 phosphorylation in vivo

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