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Tsubakihara et al., 2020

Phase II study of troxacitabine, a novel dioxolane nucleoside analog, in patients with refractory leukemia

Wash off in the morning if tending to irritate

For example, the interaction between ApoE and TREM2, another major risk factor for sporadic AD, has been reported to facilitate the uptake of A by microglia, and AD-linked mutations in TREM2 impair the binding affinity of TREM2 for ApoE leading to A accumulation in the brain (Yeh et al., 2016)