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Oxidative stress plays a crucial role in the pathogenesis of IBD, and increased levels of ROSs coupled with decreased levels of antioxidants contribute to disease pathogenesis [161,162]

Particularly, influenza vaccines, for example, activate the immune system and may trigger autoimmune thyroid disorders, particularly in individuals with a genetic or immunological predisposition

They help restore and preserve microbial diversity, particularly after disruptions caused by antibiotic use, dietary changes, or gastrointestinal diseases (9)

The benefit of improved therapeutic effect with higher doses should be weighed against the possibility of a greater incidence of adverse reactions