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Additionally, in vivo barcoding technologies, including those using adeno-associated viruses (AAVs), enable the tracking of tumor evolution in more physiologically relevant contexts [160]

Metabolic reprogramming and interventions in endometrial carcinoma

Finally, H 2 O 2 levels were significantly increased in cultured G6PDH-null chondrocytes but only during differentiation in hypoxia, indicating that the decreased NADPH:NADP + and GSH:GSSG ratios can still prevent oxidative stress during proliferation but not during differentiation, probably because redox balance is more challenged during differentiation (Fig