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You are not producing enough digestive juices and enzymes for proper digestion

Because not only does all the signaling say, do something with the cholesterol, but the way you actually get cholesterol into the cell is to burn through a bunch of ATP with motor proteins, move it from outside the cell to inside the cell in order to facilitate that turnover

This process is mediated through the upregulation of pro-apoptotic factors and the Immunoglobulin-Regulated Enhancer 1 - C/EBP-homologous protein / c-Jun N-terminal kinase pathway, achieved by suppressing Bcl-2 survival signaling, extracellular regulated protein kinases/AKT phosphorylation, CDK1/cyclin B1 complexes, and cyclooxygenase-2 (COX-2)

Yes, your appetite will be lower