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However, in diabetic individuals, this immune response is often compromised because of hyperglycemia, which impairs neutrophil function, including phagocytosis and migration, leading to ineffective pathogen clearance [19]

Diabetes Care 39 , 596602 (2016)

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Anxiety can deepen the same loop, since excessive worry often brings muscle tension, restlessness, and trouble concentrating, symptoms detailed by the Mayo Clinic in its guide to generalized anxiety disorder