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In fact, the loss of FH has been previously associated with the increased production of reactive oxygen species (ROS) 9 , and the accumulation of fumarate in FH-deficient cancer cell lines leads to the formation of an adduct between fumarate and glutathione (GSH), which depletes intracellular NADPH and enhances oxidative stress 10

A cascade of amplification between ferroptosis and immune activation was formed via the system, ultimately prohibiting tumor growth [181]

Therefore, it is not easy to decide in a simple manner which type of MS is optimal

Participa en funciones relacionadas con el sistema nervioso central