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Contraindications include active or recent cancer, uncontrolled diabetes, severe diabetic retinopathy, and pregnancy

Sources: Johansen PB, et al

A widely used research tool for studying IGF-1 receptor (IGF-1R) signal transduction including PI3K/Akt pathway activation, MAPK/ERK phosphorylation cascades, and downstream transcription factor engagement in IGF-1R-expressing cell lines