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OtolaryngologyHead and Neck Surgery

Blood J 121:8 Zanoni TB, Tiago M, Faio-Flores F, Barros SBM, Bast A, Hageman G, Oliveira DP, Maria-Engler SS (2014) Basic red 51, a permitted semipermanent hair dye, is cytotoxic to human skin cells: studies in monolayer and 3D skin model using human keratinocytes (HaCaT)

The polyethylene glycol (PEG) and polyoxyethylene (100) stearate (PEG-100 stearate) matrix gradually softened, dissolved, and released EGCG-Zn at body temperature, facilitating the maintenance of effective drug concentrations in the rectum [47,48,49,50,51]