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10.1016/j.abb.2012.04.014 Vido K, Diemer H, Van Dorsselaer A, Leize E, Juillard V, Gruss A, Gaudu P: Roles of thioredoxin reductase during the aerobic life of Lactococcus lactis

PMID: 118 RubinVNRuenitzPCBoudinotFDBoydJL

It is worth noting a point of ongoing scholarly discussion around this origin story: BPC-157, as studied, is a fully synthetic sequence, and its status as a naturally occurring fragment of a larger native protein has been questioned in later reviews

Another study showed that DFO could suppress excessive collagenase-mediated type II collagen cleavage and protease, production of cytokine, and COL10A1 expression while upregulating adenosine monophosphate-activated protein kinase and Krebs cycle genes in human osteoarthritic cartilage [125]