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When to Seek Medical Attention : Severe allergic reaction (itching, swelling, difficulty breathing) Chest pain or sudden weakness Drug Interactions : Can interfere with certain laboratory tests and may interact with medications like folic acid, requiring monitoring in some cases

Pregnant women aged 18 y who presented for prenatal care before or at 14 wk of gestational age (as judged by the date of the last menstrual period) were eligible for inclusion

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Symptoms may include: intense shoulder pain joint pain decreased arm mobility, including range of motion in the shoulder rotator cuff tendonitis bursitis arthralgia frozen shoulder weakness or altered sensation in the arm shoulder stiffness SIRVA can result in chronic or sometimes permanent injury to the arm and shoulder