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PMID: 50 RussoJMoralRBaloghGAMailoDRussoIH

Cellular mechanisms of complex I-associated pathology

doi: 10.1161/01.CIR.101.15.1767 57

The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of various organ systems, especially the eyes, kidneys, nerves, heart, and blood vessels ( Diabetic retinopathy (DR) is the most common microvascular complication of DM and is a leading cause of blindness in the working age population worldwide ( Clinically, DR is classified into two progressive stages termed non-proliferative DR (NPDR) and proliferative DR (PDR)