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Melanin distribution inhibition via Niacinamide: Niacinamide slows melanosome transfer to the skin surface, helping prevent pigment from accumulating where you most need evening out, especially on knees, elbows, and areas prone to friction

Magnesium, a mineral for muscle and nerve function also enhances bone density and preserves joint and bone health

Others like metformin and rapamycin, which are already used for diabetes or immune issues, might also help slow aging by targeting senescent cells

Duerr RH, Taylor KD, Brant SR et al (2006) A genome-wide association study identifies IL23R as an inflammatory bowel disease gene