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As much of the B12 in our diet comes from animal products, vegans are at higher risk of getting a B12 deficiency

[7] In practice, some protocols use 1 mg IM monthly for maintenance once levels are stabilized

The cryo-EM structure, resolved at approximately 3.0 angstroms, showed that orforglipron occupies a pocket within the TMD that is entirely distinct from the peptide-binding site