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The BPC-157 peptide aids in producing angiogenic growth factors like FGF, TGF-b, and VEGF

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PPI mechanistic effects included cytotoxic effects on polymorphonuclear neutrophils (PMNs), inhibition of reactive oxygen species (ROS) and reactive nitrogen species (RNS), phagocytosis and phagosomal degradation, inhibition of chemotaxis and migration, altering Toll-like receptor (TLR) signaling and p38 protein phosphorylation in immune cells, and altering neutrophil and macrophage gene expression

This review synthesizes recent advances in PPS-mediated ROS signaling modulation, systematically dissecting its molecular underpinnings and evaluating its translational prospects for anticancer drug development