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In addition, oxidative glutamate toxicity is higher than the glutamate concentration required for NMDA receptor activation (Murphy et al., 1989)

Different effects on ACC oxidase gene silencing triggered by RNA interference in transgenic tomato

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They include CAMP-response element binding protein (CREB), SP1 transcription factor (SP1), transcription factor AP-2 (AP2), proliferator-activated receptor alpha (PPAR), all activating GPX4 expression, while Krppel-like transcription factor 2 (KLF2) and CAMP-response element modulator (CREM), both repress its protein expression [7]