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Notably, the intracellular levels of NAD were decreased in 1919 PSPH amp cells, indicating a high turnover of NAD (Fig

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Additionally, copper holds a significant position among enzymes, ranking as the second most prevalent metal after zinc and contributing to their proper functioning (97)

Ornithine decarboxylase (ODC) is highly expressed in tumors including breast (221), gastric (222), and colorectal cancer (223), and its overexpression-driven excessive polyamine accumulation promotes tumor initiation and metastasis