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Saha S, Buttari B, Panieri E, Profumo E, Saso L
Ferroptosis in prostate cell lines could be aggravated by the autophagy activator Rapa, while the effects were reversed by the autophagy inhibitor CQ
On the other hand, ROS induce the binding of Src homology 2 domain-containing phosphatase 1 (SHP1) to c-Src and the oxidation of c-Src and SHP-1, which lead to SHP-1 inactivation and activation of c-Src via phosphorylation of Tyr416, contributing to osteoclast survival and increasing bone loss (226)
