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We found that extended corticosteroid treatment beyond 30 days was manageable and, importantly, helped avoid transaminase elevation, which can reduce AAV-based therapy efficiency [50]

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Finally, I review evidence-based approaches, including prolonged exposure therapy and cognitive behavioral therapy, discuss how five minutes per day of deliberate stress through cyclic hyperventilation can rewire fear responses, explain the critical role of social connection in activating neural pathways that reduce trauma, and share supplementation options for managing anxiety