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Mandato C, Siano MA, Nazzaro L, Gelzo M, Francalanci P, Rizzo F, DAgostino Y, Morleo M, Brillante S, Weisz A, et al

Adipose-derived stem cell (ADSCs) exosome-treated macrophages upregulate HO-1 expression by inhibiting Keap1 and promoting Nrf2 expression and translocation into the nucleus, thereby reducing inflammation and oxidative stress (93)

The more carbs, the harder athletes can push (relative to aerobic threshold in longer ultras, and lactate threshold in shorter events), and the more they can disrespect their endurance limits