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nevertheless, no strong pro-surfactant C staining was evident over 12-day period, suggesting that type II pneumocytes were not present, contrasting with previous findings ( Moreover, Laboratory 2 observed that, in general, the concentration related changes induced by the benchmark chemicals ranged from increased cell degeneration, separation/detachment, multifocal thinning (e.g., Crystalline silica, Amorphous silica, and Doxorubicin) and with more severe injury locally extensive cell death/necrosis (e.g., PHMG and Akemi)

EC demonstrates relatively low and variable oral bioavailability due to rapid phase II conjugation in the small intestine and liver, coupled with extensive microbial degradation in the colon (Oketch-Rabah et al., 2020)

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