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Treatment for B12 deficiency without neurological involvement: For patients with haematological manifestations only (macrocytic anaemia) or asymptomatic deficiency, the regimen is hydroxocobalamin 1mg intramuscularly three times weekly for two weeks (total of six injections), followed by maintenance of 1mg every three months for life

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432,433 Microglia may contribute to neuropathic pain through impaired descending modulation, altering the balance between descending inhibition and excitation toward the latter

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