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Its set my math brain going (my year 10 math class is doing data and graphs so its on the brain!) Interesting that they were trying to find this out back then in the 1950s

One point is where it seems to act

It reflects a deeper immune imbalance involving the IL-17 and IL-23 inflammatory pathways, gut microbiome dysbiosis, genetic predisposition (HLA-B27 and related alleles), and environmental triggers including trauma, infection, and metabolic dysfunction

While peptides are pretty well-tolerated and safe for most people, those with issues like a sensitive scalp, dermatitis or allergies should try a patch test first, Queller says