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Biotechnol Adv

MS: attending Nephrologist on the case, critically reviewed, and revised the manuscript for important intellectual content

However, if you are deficient in B12 and are experiencing anxiety as a result, taking a supplement may help alleviate your symptoms.

Previous and current PPIs use was significantly associated with the presence of vitamin B12 deficiency, respectively a two or more years treatment with PPIs was associated with a 65% increased risk for vitamin B12 deficiency (OR, 1.65 [95% CI, 1.58-1.73]) (Lam et al