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Purity: 99.38% CAS No.: 122323-88-0 Formula: C 6 H 14 Cl 2 N 2 O 2 Molecular Weight:217.09 Storage: Store at room temperature, keep dry and cool

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Disclosures: Thi Nga Ha: Nothing to Disclose, Hyon-Seung Yi: Nothing to Disclose, Dong Wook Choi: Nothing to Disclose 1992 HEPATOCYTE-DERIVED FIBROBLAST GROWTH FACTOR 18 PROMOTES HEPATIC FIBROGENESIS UNDER DIETARY STEATOHEPATITIS IN HEPATOCYTE-SPECIFIC CFLAR DEFICIENT MICE Kyoko Fukuhara 1 Yuichi Tsuchiya 2 SHUNHEI YAMASHINA 1 Xingchen Liu 1 Kazuyoshi Kon 1 Akira Uchiyama 1 Reiko Yaginuma 1 Kei Ishizuka 1 Hiroyasu Nakano 3 Kenichi Ikejima 1 , 1 Juntendo University School of Medicine, 2 Department of Biochemistry Toho University Faculty of Pharmaceutical sciences, 3 Department of Biochemistry Toho University School of Medicine Background: Fibroblast growth factors (FGFs) play a pivotal role in tissue remodeling through regulation of various cellular responses such as proliferation, survival, migration and differentiation