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However, glucagon in CNS decreases food intake, increases energy expenditure via brown fat thermogenesis, decreases fat accumulation via lipolysis and lipid synthesis inhibition, improves cardiac performance, inhibits gastric motility, and stimulates autophagy

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For example, although Piezo1 promotes the growth and development of oligodendrocytes (OPCs) and oligodendrocyte progenitor cells in the human brain, its expression decreases with in vitro maturation of MO3.13 oligodendrocytes (Velasco-Estevez et al., 2022)